Co-expression analysis reveals interpretable gene modules controlled by trans-acting genetic variants

Understanding the causal processes that contribute to disease onset and progression is essential for developing novel therapies. Although trans-acting expression quantitative trait loci (trans-eQTLs) can directly reveal cellular processes modulated by disease variants, detecting trans-eQTLs remains...

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Bibliographic Details
Main Authors: Liis Kolberg, Nurlan Kerimov, Hedi Peterson, Kaur Alasoo
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/58705