Robust Filtering and Noise Suppression in Intragenic miRNA-Mediated Host Regulation

Summary: MicroRNAs (miRNAs) are short non-coding RNA molecules that regulate gene expression post-transcriptionally by binding to target messenger RNAs (mRNAs). Many human miRNAs are intragenic, located within introns of protein-coding sequence (host). Intriguingly, a percentage of intragenic miRNAs...

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Bibliographic Details
Main Authors: Taek Kang, Tyler Quarton, Chance M. Nowak, Kristina Ehrhardt, Abhyudai Singh, Yi Li, Leonidas Bleris
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220307872