Chemokine CXCL13 in serum, CSF and blood–CSF barrier function: evidence of compartment restriction
Abstract Background and purpose Elevation of the chemokine CXCL13 in CSF frequently occurs during active and acute CNS inflammatory processes and presumably is associated with B cell-related immune activation. Elevation levels, however, vary a lot and “leaking” of CXCL13 from blood across dysfunctio...
Main Authors: | Georg Pilz, Irma Sakic, Peter Wipfler, Jörg Kraus, Elisabeth Haschke-Becher, Wolfgang Hitzl, Eugen Trinka, Andrea Harrer |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-02-01
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Series: | Fluids and Barriers of the CNS |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12987-020-0170-5 |
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