Chemokine CXCL13 in serum, CSF and blood–CSF barrier function: evidence of compartment restriction

Chemokine CXCL13 in serum, CSF and blood–CSF barrier function: evidence of compartment restriction

Abstract Background and purpose Elevation of the chemokine CXCL13 in CSF frequently occurs during active and acute CNS inflammatory processes and presumably is associated with B cell-related immune activation. Elevation levels, however, vary a lot and “leaking” of CXCL13 from blood across dysfunctio...

Full description

Bibliographic Details
Main Authors: Georg Pilz, Irma Sakic, Peter Wipfler, Jörg Kraus, Elisabeth Haschke-Becher, Wolfgang Hitzl, Eugen Trinka, Andrea Harrer
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Fluids and Barriers of the CNS
Subjects:
Chemokine
CXCL13
Cerebrospinal fluid
Blood–CSF-barrier
Inflammation
Biomarker
Online Access:http://link.springer.com/article/10.1186/s12987-020-0170-5

Internet

http://link.springer.com/article/10.1186/s12987-020-0170-5

Similar Items