Assessing Diffusion in the Extra-Cellular Space of Brain Tissue by Dynamic MRI Mapping of Contrast Agent Concentrations

The characterization of extracellular space (ECS) architecture represents valuable information for the understanding of transport mechanisms occurring in brain parenchyma. ECS tortuosity reflects the hindrance imposed by cell membranes to molecular diffusion. Numerous strategies have been proposed t...

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Bibliographic Details
Main Authors: Sébastien Mériaux, Allegra Conti, Benoît Larrat
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Physics
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fphy.2018.00038/full