In vivo suppression of HIV by antigen specific T cells derived from engineered hematopoietic stem cells.

In vivo suppression of HIV by antigen specific T cells derived from engineered hematopoietic stem cells.

The HIV-specific cytotoxic T lymphocyte (CTL) response is a critical component in controlling viral replication in vivo, but ultimately fails in its ability to eradicate the virus. Our intent in these studies is to develop ways to enhance and restore the HIV-specific CTL response to allow long-term...

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Bibliographic Details
Main Authors: Scott G Kitchen, Bernard R Levin, Gregory Bristol, Valerie Rezek, Sohn Kim, Christian Aguilera-Sandoval, Arumugam Balamurugan, Otto O Yang, Jerome A Zack
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3325196?pdf=render

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http://europepmc.org/articles/PMC3325196?pdf=render

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