Pathophysiological Significance of Store-Operated Calcium Entry in Megakaryocyte Function: Opening New Paths for Understanding the Role of Calcium in Thrombopoiesis

Pathophysiological Significance of Store-Operated Calcium Entry in Megakaryocyte Function: Opening New Paths for Understanding the Role of Calcium in Thrombopoiesis

Store-Operated Calcium Entry (SOCE) is a universal calcium (Ca2+) influx mechanism expressed by several different cell types. It is now known that Stromal Interaction Molecule (STIM), the Ca2+ sensor of the intracellular compartments, together with Orai and Transient Receptor Potential Canonical (TR...

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Bibliographic Details
Main Authors: Christian A. Di Buduo, Alessandra Balduini, Francesco Moccia
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Series:International Journal of Molecular Sciences
Subjects:
megakaryocyte
platelet production
calcium
SOCE
calreticulin
myelofibrosis
Online Access:http://www.mdpi.com/1422-0067/17/12/2055

Internet

http://www.mdpi.com/1422-0067/17/12/2055

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