Role of HK2 in the Enzootic Cycle of Borrelia burgdorferi

The two-component response regulator Rrp2 is a key activator controlling the production of numerous virulence factors of Borrelia burgdorferi, the Lyme disease pathogen. Previously it was shown that the cognate histidine kinase HK2 is not required for Rrp2 activation in vitro, nor for mammalian infe...

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Bibliographic Details
Main Authors: Qiang Liu, Haijun Xu, Yan Zhang, Jing Yang, Jimei Du, Yan Zhou, X. Frank Yang, Yongliang Lou
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2020.573648/full