Amorphous Nanosuspensions Aggregated from Paclitaxel–Hemoglobulin Complexes with Enhanced Cytotoxicity

Amorphous Nanosuspensions Aggregated from Paclitaxel–Hemoglobulin Complexes with Enhanced Cytotoxicity

Amorphous nanosuspensions (ANSs) enable rapid release and improved delivery of a poorly water-soluble drug; however, their preparation is challenging. Here, using hemoglobin (Hb) as a carrier, ANSs aggregated from paclitaxel (PTX)–Hb complexes were prepared to improve delivery of the hydro...

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Bibliographic Details
Main Authors: Chao Qin, Xiaofei Xin, Xue Pei, Lifang Yin, Wei He
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Pharmaceutics
Subjects:
nanosuspensions
amorphous
affinity
drug-protein complexes
cytotoxicity
Online Access:http://www.mdpi.com/1999-4923/10/3/92

Internet

http://www.mdpi.com/1999-4923/10/3/92

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