The amino acid transporter SLC7A5 confers a poor prognosis in the highly proliferative breast cancer subtypes and is a key therapeutic target in luminal B tumours

The amino acid transporter SLC7A5 confers a poor prognosis in the highly proliferative breast cancer subtypes and is a key therapeutic target in luminal B tumours

Abstract Background Breast cancer (BC) is a heterogeneous disease characterised by variant biology and patient outcome. The amino acid transporter, SLC7A5, plays a role in BC although its impact on patient outcome in different BC subtypes remains to be validated. This study aimed to determine whethe...

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Bibliographic Details
Main Authors: Rokaya El Ansari, Madeleine L. Craze, Islam Miligy, Maria Diez-Rodriguez, Christopher C. Nolan, Ian O. Ellis, Emad A. Rakha, Andrew R. Green
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Breast Cancer Research
Subjects:
SLC7A5
Breast cancer
Prognosis
Online Access:http://link.springer.com/article/10.1186/s13058-018-0946-6

Internet

http://link.springer.com/article/10.1186/s13058-018-0946-6

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