The prima donna of epigenetics: the regulation of gene expression by DNA methylation

This review focuses on the mechanisms of DNA methylation, DNA methylation pattern formation and their involvement in gene regulation. Association of DNA methylation with imprinting, embryonic development and human diseases is discussed. Furthermore, besides considering changes in DNA methylation as...

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Bibliographic Details
Main Authors: K.F. Santos, T.N. Mazzola, H.F. Carvalho
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2005-10-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005001000010