Layer 6b Is Driven by Intracortical Long-Range Projection Neurons

Summary: Layer 6b (L6b), the deepest neocortical layer, projects to cortical targets and higher-order thalamus and is the only layer responsive to the wake-promoting neuropeptide orexin/hypocretin. These characteristics suggest that L6b can strongly modulate brain state, but projections to L6b and t...

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Bibliographic Details
Main Authors: Timothy A. Zolnik, Julia Ledderose, Maria Toumazou, Thorsten Trimbuch, Tess Oram, Christian Rosenmund, Britta J. Eickholt, Robert N.S. Sachdev, Matthew E. Larkum
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720302059