Study of the molecular recognition of aptamers selected through ovarian cancer cell-SELEX.

Ovarian cancer is the most lethal gynecological malignancy, and the ovarian clear cell carcinoma subtype (OCCA) demonstrates a particularly poor response to standard treatment. Improvements in ovarian cancer outcomes, especially for OCCA, could be expected from a clearer understanding of the molecul...

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Bibliographic Details
Main Authors: Dimitri Van Simaeys, Dalia López-Colón, Kwame Sefah, Rebecca Sutphen, Elizabeth Jimenez, Weihong Tan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2967474?pdf=render