Regulatory T Cell Extracellular Vesicles Modify T-Effector Cell Cytokine Production and Protect Against Human Skin Allograft Damage

Regulatory T Cell Extracellular Vesicles Modify T-Effector Cell Cytokine Production and Protect Against Human Skin Allograft Damage

Regulatory T cells (Tregs) are a subpopulation of CD4+ T cells with a fundamental role in maintaining immune homeostasis and inhibiting unwanted immune responses using several different mechanisms. Recently, the intercellular transfer of molecules between Tregs and their target cells has been shown...

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Bibliographic Details
Main Authors: Sim Lai Tung, Giorgia Fanelli, Robert Ian Matthews, Jordan Bazoer, Marilena Letizia, Gema Vizcay-Barrena, Farid N. Faruqu, Christina Philippeos, Rosalind Hannen, Khuloud T. Al-Jamal, Giovanna Lombardi, Lesley Ann Smyth
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Regulatory T (Treg) cells
extracellular vesicles
cytokines
allograft rejection
miRNA – microRNA
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00317/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00317/full

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