The expression and activity of cathepsins D, H and K in asthmatic airways.

The expression and activity of cathepsins D, H and K in asthmatic airways.

Tumstatin is an anti-angiogenic collagen IV α3 fragment, levels of which are reduced in the airways of asthmatics. Its reduction may be due to the degradation by extracellular matrix (ECM) proteases. Cathepsins play a role in ECM remodelling, with cathepsin D, H and K (CTSD, CTSH and CTSK) being ass...

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Bibliographic Details
Main Authors: Alen Faiz, Gavin Tjin, Louise Harkness, Markus Weckmann, Shisan Bao, Judith L Black, Brian G G Oliver, Janette K Burgess
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3590183?pdf=render

Internet

http://europepmc.org/articles/PMC3590183?pdf=render

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