Transcription factor 4 and its association with psychiatric disorders
Abstract The human transcription factor 4 gene (TCF4) encodes a helix–loop–helix transcription factor widely expressed throughout the body and during neural development. Mutations in TCF4 cause a devastating autism spectrum disorder known as Pitt–Hopkins syndrome, characterized by a range of aberran...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-01-01
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Series: | Translational Psychiatry |
Online Access: | https://doi.org/10.1038/s41398-020-01138-0 |