MR CLEAN-NO IV: intravenous treatment followed by endovascular treatment versus direct endovascular treatment for acute ischemic stroke caused by a proximal intracranial occlusion—study protocol for a randomized clinical trial

MR CLEAN-NO IV: intravenous treatment followed by endovascular treatment versus direct endovascular treatment for acute ischemic stroke caused by a proximal intracranial occlusion—study protocol for a randomized clinical trial

Abstract Background Endovascular treatment (EVT) has greatly improved the prognosis of acute ischemic stroke (AIS) patients with a proximal intracranial large vessel occlusion (LVO) of the anterior circulation. Currently, there is clinical equipoise concerning the added benefit of intravenous altepl...

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Bibliographic Details
Main Authors: Kilian M. Treurniet, Natalie E. LeCouffe, Manon Kappelhof, Bart J. Emmer, Adriaan C. G. M. van Es, Jelis Boiten, Geert J. Lycklama, Koos Keizer, Lonneke S. F. Yo, Hester F. Lingsma, Wim H. van Zwam, Inger de Ridder, Robert J. van Oostenbrugge, Aad van der Lugt, Diederik W. J. Dippel, Jonathan M. Coutinho, Yvo B. W. E. M. Roos, Charles B. L. M. Majoie, for the MR CLEAN-NO IV Investigators
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Trials
Subjects:
Intravenous alteplase
Endovascular treatment
Ischemic stroke
Online Access:https://doi.org/10.1186/s13063-021-05063-5

Internet

https://doi.org/10.1186/s13063-021-05063-5

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