Targeted Inhibition of Multiple Receptor Tyrosine Kinases in Mesothelioma

Targeted Inhibition of Multiple Receptor Tyrosine Kinases in Mesothelioma

The receptor tyrosine kinases (RTKs) epidermal growth factor receptor (EGFR) and MET are activated in subsets of mesothelioma, suggesting that these kinases might represent novel therapeutic targets in this notoriously chemotherapy-resistant cancer. However, clinical trials have shown little activi...

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Bibliographic Details
Main Authors: Wen-Bin Ou, Christopher Hubert, Jonathan A. Fletcher, Joseph M. Corson, Raphael Bueno, Daniel L. Flynn, David J. Sugarbaker
Format: Article
Language:English
Published: Elsevier 2011-01-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558611801077

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http://www.sciencedirect.com/science/article/pii/S1476558611801077

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