N-Acetylcysteine Nanocarriers Protect against Oxidative Stress in a Cellular Model of Parkinson’s Disease

N-Acetylcysteine Nanocarriers Protect against Oxidative Stress in a Cellular Model of Parkinson’s Disease

Oxidative stress is a key mediator in the development and progression of Parkinson’s disease (PD). The antioxidant n-acetylcysteine (NAC) has generated interest as a disease-modifying therapy for PD but is limited due to poor bioavailability, a short half-life, and limited access to the brain. The a...

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Bibliographic Details
Main Authors: Leah Mursaleen, Brendon Noble, Stefanie Ho Yi Chan, Satyanarayana Somavarapu, Mohammed Gulrez Zariwala
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Antioxidants
Subjects:
n-acetylcysteine
oxidative stress
Parkinson’s disease
neurodegeneration
antioxidant capacity
deferoxamine
Online Access:https://www.mdpi.com/2076-3921/9/7/600

Internet

https://www.mdpi.com/2076-3921/9/7/600

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