Gene Regulatory Network Rewiring in the Immune Cells Associated with Cancer

The gene regulatory networks (GRNs) of immune cells not only indicate cell identity but also reveal the dynamic changes of immune cells when comparing their GRNs. Cancer immunotherapy has advanced in the past few years. Immune-checkpoint blockades (i.e., blocking PD-1, PD-L1, or CTLA-4) have shown d...

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Bibliographic Details
Main Authors: Pengyong Han, Chandrasekhar Gopalakrishnan, Haiquan Yu, Edwin Wang
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/8/11/308