Co-translational protein targeting facilitates centrosomal recruitment of PCNT during centrosome maturation in vertebrates

Co-translational protein targeting facilitates centrosomal recruitment of PCNT during centrosome maturation in vertebrates

As microtubule-organizing centers of animal cells, centrosomes guide the formation of the bipolar spindle that segregates chromosomes during mitosis. At mitosis onset, centrosomes maximize microtubule-organizing activity by rapidly expanding the pericentriolar material (PCM). This process is in part...

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Bibliographic Details
Main Authors: Guadalupe Sepulveda, Mark Antkowiak, Ingrid Brust-Mascher, Karan Mahe, Tingyoung Ou, Noemi M Castro, Lana N Christensen, Lee Cheung, Xueer Jiang, Daniel Yoon, Bo Huang, Li-En Jao
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-04-01
Series:eLife
Subjects:
centrosome
mRNA localization
translation
Online Access:https://elifesciences.org/articles/34959

Internet

https://elifesciences.org/articles/34959

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