A humanized leucine zipper-TRAIL hybrid induces apoptosis of tumors both in vitro and in vivo.
Evidence suggests that stimulating apoptosis in malignant cells without inflicting collateral damage to the host's normal tissues is a promising cancer therapy. Chemo- and radiation therapies that, especially if combined, induce apoptosis in tumor cells have been used for treating cancer patien...
Main Authors: | Dmitri Rozanov, Paul Spellman, Alexei Savinov, Alex Y Strongin |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4388654?pdf=render |
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