Hippocampal CA3 transcriptome signature correlates with initial precipitating injury in refractory mesial temporal lobe epilepsy.

Hippocampal CA3 transcriptome signature correlates with initial precipitating injury in refractory mesial temporal lobe epilepsy.

BACKGROUND: Prolonged febrile seizures constitute an initial precipitating injury (IPI) commonly associated with refractory mesial temporal lobe epilepsy (RMTLE). In order to investigate IPI influence on the transcriptional phenotype underlying RMTLE we comparatively analyzed the transcriptomic sign...

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Bibliographic Details
Main Authors: Silvia Y Bando, Maryana C Alegro, Edson Amaro, Alexandre V Silva, Luiz H M Castro, Hung-Tzu Wen, Leandro de A Lima, Helena Brentani, Carlos Alberto Moreira-Filho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3194819?pdf=render

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http://europepmc.org/articles/PMC3194819?pdf=render

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