Spatial and functional aspects of ER-Golgi Rabs and tethers
Two conserved Rab GTPases, Rab1 and Rab2, play important roles in biosynthetic-secretory trafficking between the endoplasmic reticulum (ER) and the Golgi apparatus in mammalian cells. Both are expressed as two isoforms that regulate anterograde transport via the intermediate compartment (IC) to the...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2016-04-01
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Series: | Frontiers in Cell and Developmental Biology |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fcell.2016.00028/full |