Serum ferritin and ECOG performance status predict the response and improve the prognostic value of IPSS or IPSS-R in patients with high-risk myelodysplastic syndromes and oligoblastic acute myeloid leukemia treated with 5-azacytidine: a retrospective analysis of the Hellenic national registry of myelodysplastic and hypoplastic syndromes

Background: 5-azacytidine (5-AZA) improves survival of patients with higher-risk myelodysplastic syndromes (MDSs) and oligoblastic acute myeloid leukemia (AML); however, predictive factors for response and outcome have not been consistently studied. Methods: This study of the Hellenic MDS Study Grou...

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Main Authors: Sotirios G. Papageorgiou, Ioannis Kotsianidis, Anthi Bouchla, Argyris Symeonidis, Athanasios Galanopoulos, Nora-Athina Viniou, Eleftheria Hatzimichael, Theodoros P. Vassilakopoulos, Dimitrios Gogos, Aikaterini Megalakaki, Panagiotis Zikos, Panagiotis Diamantopoulos, Alexandra Kourakli, Panagiota Giannoulia, Menelaos Papoutselis, Elias Poulakidas, Maria Arapaki, Anna Vardi, Achilles Anagnostopoulos, Despoina Mparmparousi, Maria Papaioannou, Eleni Bouronikou, Maria Dimou, Helen Papadaki, Panayiotis Panayiotidis, Vasiliki Pappa
Format: Article
Language:English
Published: SAGE Publishing 2020-12-01
Series:Therapeutic Advances in Hematology
Online Access:https://doi.org/10.1177/2040620720966121