Protocol to Generate and Characterize Potent and Selective WNT Mimetic Molecules
SUMMARY: WNT signaling is crucial for embryonic development, adult tissue homeostasis, and injury repair. The poor biophysical characteristics of WNTs and their lack of receptor selectivity have hindered their use as research tools or potential therapeutics. We have developed a platform to generate...
Main Authors: | Hui Chen, Chenggang Lu, Sung-Jin Lee, Yang Li |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-06-01
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Series: | STAR Protocols |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666166720300307 |
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