Activity and Trafficking of Copper-Transporting ATPases in Tumor Development and Defense against Platinum-Based Drugs

Membrane trafficking pathways emanating from the Golgi regulate a wide range of cellular processes. One of these is the maintenance of copper (Cu) homeostasis operated by the Golgi-localized Cu-transporting ATPases ATP7A and ATP7B. At the Golgi, these proteins supply Cu to newly synthesized enzymes...

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Bibliographic Details
Main Authors: Raffaella Petruzzelli, Roman S. Polishchuk
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/9/1080