Generating Ensembles of Gene Regulatory Networks to Assess Robustness of Disease Modules

The use of biological networks such as protein–protein interaction and transcriptional regulatory networks is becoming an integral part of genomics research. However, these networks are not static, and during phenotypic transitions like disease onset, they can acquire new “communities” (or highly in...

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Bibliographic Details
Main Authors: James T. Lim, Chen Chen, Adam D. Grant, Megha Padi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.603264/full