Development and Validation of UHPLC-MS/MS Assay for Therapeutic Drug Monitoring of High-dose Methotrexate in Children with Acute Lymphoblastic Leukemia

Le-jing Lian,1 Bin Lin,2 Xiao Cui,1 Jie He,1 Zhe Wang,1 Xiao-dong Lin,1 Wei-jian Ye,1 Rui-jie Chen,1 Wei Sun1 1Department of Pharmacy, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou 325027, People’s Republic of China; 2Departm...

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Bibliographic Details
Main Authors: Lian LJ, Lin B, Cui X, He J, Wang Z, Lin XD, Ye WJ, Chen RJ, Sun W
Format: Article
Language:English
Published: Dove Medical Press 2020-11-01
Series:Drug Design, Development and Therapy
Subjects:
Online Access:https://www.dovepress.com/development-and-validation-of-uhplc-msms-assay-for-therapeutic-drug-mo-peer-reviewed-article-DDDT