Mitochondrial DNA sequence variation and neurodegeneration

<p>Abstract</p> <p>Mitochondria, the powerhouse of the cell, play a critical role in several metabolic processes and apoptotic pathways. Many lines of evidence suggest that mitochondria have a central role in ageing-related neurodegenerative diseases. Moreover, there is a long hist...

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Bibliographic Details
Main Authors: Mancuso Michelangelo, Filosto Massimiliano, Orsucci Daniele, Siciliano Gabriele
Format: Article
Language:English
Published: BMC 2008-09-01
Series:Human Genomics
Subjects:
Online Access:http://www.humgenomics.com/content/3/1/71