Smooth muscle-specific HuR knockout induces defective autophagy and atherosclerosis

Abstract Human antigen R (HuR) is a widespread RNA-binding protein involved in homeostatic regulation and pathological processes in many diseases. Atherosclerosis is the leading cause of cardiovascular disease and acute cardiovascular events. However, the role of HuR in atherosclerosis remains unkno...

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Bibliographic Details
Main Authors: Shanshan Liu, Xiuxin Jiang, Xiuru Cui, Jingjing Wang, Shangming Liu, Hongxuan Li, Jianmin Yang, Cheng Zhang, Wencheng Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03671-2