Physico-chemical characterization of bilirubin-10-sulfonate and comparison of its acid–base behavior with unconjugated bilirubin

Physico-chemical characterization of bilirubin-10-sulfonate and comparison of its acid–base behavior with unconjugated bilirubin

Abstract Unconjugated bilirubin (UCB) is the end-product of heme catabolism in the intravascular compartment. Although beneficial for human health when mildly elevated in the body, when present at greater than a critical threshold concentration, UCB exerts toxic effects that are related to its physi...

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Bibliographic Details
Main Authors: Adam Čepa, Veronika Dejmková, Ladislav Lešetický, Ivan Jelínek, Stanislav Smrček, Martin Štícha, Jana Jašprová, Marie Urbanová, Iryna Goncharova, Martin Dračínský, Eliška Procházková, Donald J. Ostrow, Libor Vítek
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92377-8

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https://doi.org/10.1038/s41598-021-92377-8

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