Increased Intrathecal Immune Activation in Virally Suppressed HIV-1 Infected Patients with Neurocognitive Impairment.

OBJECTIVE:Although milder forms of HIV-associated neurocognitive disorder (HAND) remain prevalent, a correlation to neuronal injury has not been established in patients on antiretroviral therapy (ART). We examined the relationship between mild HAND and CSF neurofilament light protein (NFL), a biomar...

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Bibliographic Details
Main Authors: Arvid Edén, Thomas D Marcotte, Robert K Heaton, Staffan Nilsson, Henrik Zetterberg, Dietmar Fuchs, Donald Franklin, Richard W Price, Igor Grant, Scott L Letendre, Magnus Gisslén
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4905676?pdf=render