PLEK2 promotes gallbladder cancer invasion and metastasis through EGFR/CCL2 pathway

PLEK2 promotes gallbladder cancer invasion and metastasis through EGFR/CCL2 pathway

Abstract Background Gallbladder cancer (GBC) is an extremely malignant tumor with a high mortality rate. Little is known about its invasion and metastasis mechanism so far. Methods To identify the driver genes in GBC metastasis, we performed a mRNA microarray of metastatic GBC and paired non-tumor s...

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Bibliographic Details
Main Authors: Hui Shen, Min He, Ruirong Lin, Ming Zhan, Sunwang Xu, Xince Huang, Chu Xu, Wei Chen, Yanhua Yao, Man Mohan, Jian Wang
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
PLEK2
EGFR
CCL2
Metastasis
Gallbladder Cancer
Online Access:http://link.springer.com/article/10.1186/s13046-019-1250-8

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http://link.springer.com/article/10.1186/s13046-019-1250-8

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