The serine 814 of TRPC6 is phosphorylated under unstimulated conditions.

TRPC are nonselective cation channels involved in calcium entry. Their regulation by phosphorylation has been shown to modulate their routing and activity. TRPC6 activity increases following phosphorylation by Fyn, and is inhibited by protein kinase G and protein kinase C. A previous study by our gr...

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Bibliographic Details
Main Authors: Simon M Bousquet, Michael Monet, Guylain Boulay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3063223?pdf=render