Identification of isoxsuprine hydrochloride as a neuroprotectant in ischemic stroke through cell-based high-throughput screening.

Identification of isoxsuprine hydrochloride as a neuroprotectant in ischemic stroke through cell-based high-throughput screening.

Stroke is a leading cause of death and disability and treatment options are limited. A promising approach to accelerate the development of new therapeutics is the use of high-throughput screening of chemical libraries. Using a cell-based high-throughput oxygen-glucose deprivation (OGD) model, we eva...

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Bibliographic Details
Main Authors: Jeff W Hill, Jeffrey F Thompson, Mark B Carter, Bruce S Edwards, Larry A Sklar, Gary A Rosenberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4013073?pdf=render

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http://europepmc.org/articles/PMC4013073?pdf=render

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