A new approach of modified submerged patch clamp recording reveals interneuronal dynamics during epileptiform oscillations

Traditionally, visually-guided patch clamp in brain slices using submerged recording conditions has been required to characterise the activity of individual neurons. However, due to limited oxygen availability, submerged conditions truncate fast network oscillations including epileptiform activity....

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Bibliographic Details
Main Authors: Gareth Morris, Premysl Jiruska, John Gordon Ralph Jefferys, Andrew D Powell
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Neuroscience
Subjects:
LFP
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00519/full