CoQ10 Deficiency May Indicate Mitochondrial Dysfunction in Cr(VI) Toxicity

CoQ10 Deficiency May Indicate Mitochondrial Dysfunction in Cr(VI) Toxicity

To investigate the toxic mechanism of hexavalent chromium Cr(VI) and search for an antidote for Cr(VI)-induced cytotoxicity, a study of mitochondrial dysfunction induced by Cr(VI) and cell survival by recovering mitochondrial function was performed. In the present study, we found that the gene expre...

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Bibliographic Details
Main Authors: Xiali Zhong, Xing Yi, Rita de Cássia da Silveira e Sá, Yujing Zhang, Kaihua Liu, Fang Xiao, Caigao Zhong
Format: Article
Language:English
Published: MDPI AG 2017-04-01
Series:International Journal of Molecular Sciences
Subjects:
hexavalent chromium Cr(VI)
coenzyme Q10
reactive oxygen species (ROS)
mitochondrial membrane potential (MMP)
L-02 hepatocytes
apoptosis
Online Access:http://www.mdpi.com/1422-0067/18/4/816

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http://www.mdpi.com/1422-0067/18/4/816

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