Method for the simulation of blood platelet shape and its evolution during activation.

We present a simple physically based quantitative model of blood platelet shape and its evolution during agonist-induced activation. The model is based on the consideration of two major cytoskeletal elements: the marginal band of microtubules and the submembrane cortex. Mathematically, we consider t...

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Bibliographic Details
Main Authors: Alexander E Moskalensky, Maxim A Yurkin, Artem R Muliukov, Alena L Litvinenko, Vyacheslav M Nekrasov, Andrei V Chernyshev, Valeri P Maltsev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-03-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5860797?pdf=render