Downregulation of HuR as a new mechanism of doxorubicin resistance in breast cancer cells

Downregulation of HuR as a new mechanism of doxorubicin resistance in breast cancer cells

<p>Abstract</p> <p>Background</p> <p>HuR, an RNA binding protein involved in the post-transcriptional regulation of a wide spectrum of mRNAs, has been demonstrated to be a determinant of carcinogenesis and tumor aggressiveness in several cancer types. In this study, we...

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Bibliographic Details
Main Authors: Latorre Elisa, Tebaldi Toma, Viero Gabriella, Spartà Antonino, Quattrone Alessandro, Provenzani Alessandro
Format: Article
Language:English
Published: BMC 2012-03-01
Series:Molecular Cancer
Subjects:
HuR
Doxorubicin
Drug resistance
Apoptosis
Translational regulation
Online Access:http://www.molecular-cancer.com/content/11/1/13

Internet

http://www.molecular-cancer.com/content/11/1/13

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