Memory T cell, exhaustion, and tumor immunity
CD8+T cells are important in protective immunity against intracellular pathogens and tumors. In chronic infections or cancer, CD8+T cells are constantly exposed to antigens and inflammatory signals. Such excessive and constitutive signals lead to the deterioration of T cell function, called ‘exhaust...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2020-01-01
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Series: | Immunological Medicine |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/25785826.2019.1698261 |