Manganese Inhalation as a Parkinson Disease Model

The present study examines the effects of divalent and trivalent Manganese (Mn2+/Mn3+) mixture inhalation on mice to obtain a novel animal model of Parkinson disease (PD) inducing bilateral and progressive dopaminergic cell death, correlate those alterations with motor disturbances, and determine wh...

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Bibliographic Details
Main Authors: José Luis Ordoñez-Librado, Verónica Anaya-Martínez, Ana Luisa Gutierrez-Valdez, Laura Colín-Barenque, Enrique Montiel-Flores, Maria Rosa Avila-Costa
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Parkinson's Disease
Online Access:http://dx.doi.org/10.4061/2011/612989