Schistosoma egg antigens suppress LPS-induced inflammation in human IMR-90 cells by modulation of JAK/STAT1 signaling

Schistosoma egg antigens suppress LPS-induced inflammation in human IMR-90 cells by modulation of JAK/STAT1 signaling

Background: The regulation of the balance between inflammatory and anti-inflammatory events during the treatment of pulmonary infection is very important. Soluble Schistosoma egg antigens (SEA) can effectively inhibit the expression of cytokines during hepatic acute inflammation. However, the mechan...

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Bibliographic Details
Main Authors: Kang-Yun Lee, Yi-Lin Lee, Ming-Hsiu Chiang, Hung-Yang Wang, Chong-Yu Chen, Chang-Hong Lin, Ying-Chou Chen, Chia-Kwung Fan, Po-Ching Cheng
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Journal of Microbiology, Immunology and Infection
Subjects:
Schistosoma egg antigens
Pneumonia
JAK-STAT1 pathway
Anti-inflammation
STAT1 inhibitor
Online Access:http://www.sciencedirect.com/science/article/pii/S1684118220300013

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http://www.sciencedirect.com/science/article/pii/S1684118220300013

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