Triptolide inhibits TGF-β-induced matrix contraction and fibronectin production mediated by human Tenon fibroblasts

Triptolide inhibits TGF-β-induced matrix contraction and fibronectin production mediated by human Tenon fibroblasts

AIM: To determine if triptolide influences the contractility and fibronectin production in human Tenon fibroblasts (HTFs). METHODS: HTFs were cultured in type I collagen gels with or without transforming growth factor beta (TGF-β) and/or triptolide. The diameter of the collagen gel was used to meas...

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Bibliographic Details
Main Authors: Yang Liu, Ping-Ping Liu, Lei Liu, Xiao-Shuo Zheng, Hui Zheng, Cheng-Cheng Yang, Ci-Ren Luobu, Ye Liu
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2018-07-01
Series:International Journal of Ophthalmology
Subjects:
1113
Tenon fibroblast
triptolide
transforming growth factor β
wound healing
fibronectin
Online Access:http://www.ijo.cn/en_publish/2018/7/20180706.pdf

Internet

http://www.ijo.cn/en_publish/2018/7/20180706.pdf

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