Gelsolin induces colorectal tumor cell invasion via modulation of the urokinase-type plasminogen activator cascade.

Gelsolin induces colorectal tumor cell invasion via modulation of the urokinase-type plasminogen activator cascade.

Gelsolin is a cytoskeletal protein which participates in actin filament dynamics and promotes cell motility and plasticity. Although initially regarded as a tumor suppressor, gelsolin expression in certain tumors correlates with poor prognosis and therapy-resistance. In vitro, gelsolin has anti-apop...

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Bibliographic Details
Main Authors: Jingli Zhuo, Ee Hong Tan, Benedict Yan, Lalchhandami Tochhawng, Manikandan Jayapal, Shiuan Koh, Hwee Kee Tay, Sutherland K Maciver, Shing Chuan Hooi, Manuel Salto-Tellez, Alan Prem Kumar, Yaw Chong Goh, Yaw Chyn Lim, Celestial T Yap
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3424201?pdf=render

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http://europepmc.org/articles/PMC3424201?pdf=render

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