Plasma heme oxygenase-1 levels distinguish latent or successfully treated human tuberculosis from active disease.

Tuberculosis (TB) is associated with oxidative stress and the induction of host anti-oxidants to counteract this response. Heme oxygenase-1 (HO-1) is a critical promoter of cytoprotection in diverse disease models including mycobacterial infection. Nevertheless, the pattern of expression of HO-1 in...

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Main Authors: Bruno B Andrade, Nathella Pavan Kumar, Katrin D Mayer-Barber, Daniel L Barber, Rathinam Sridhar, Vaithilingam V Banu Rekha, Mohideen S Jawahar, Thomas B Nutman, Alan Sher, Subash Babu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3646008?pdf=render