Anesthesia-induced developmental neurodegeneration: the role of neuronal organelles

Anesthesia-induced developmental neurodegeneration: the role of neuronal organelles

Exposure to general anesthetics and antiepileptics during critical stages of brain development causes significant neurotoxicity to immature neurons. Many animal, and emerging human studies have shown long-term functional sequelae manifested as behavioral deficits and cognitive impairments. Since g...

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Bibliographic Details
Main Authors: Vesna eJevtovic-Todorovic, Annalisa eBoscolo, Victoria eSanchez, Nadia eLunardi
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-10-01
Series:Frontiers in Neurology
Subjects:
Autophagy
Endoplasmic Reticulum
Mitochondria
immature brain
cognitive impairment
General Anesthetics
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2012.00141/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fneur.2012.00141/full

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