Gut Microbiome Alters the Activity of Liver Cytochromes P450 in Mice With Sex-Dependent Differences

Sexual differences and the composition/function of the gut microbiome are not considered the most important players in the drug metabolism field; however, from the recent data it is obvious that they may significantly affect the response of the patient to therapy. Here, we evaluated the effect of mi...

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Bibliographic Details
Main Authors: Lenka Jourová, Marketa Vavreckova, Nina Zemanova, Pavel Anzenbacher, Katerina Langova, Petra Hermanova, Tomas Hudcovic, Eva Anzenbacherova
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01303/full