Dietary Synbiotic Supplementation Protects Barrier Integrity of Hepatocytes and Liver Sinusoidal Endothelium in a Mouse Model of Chronic-Binge Ethanol Exposure

Alcohol overconsumption disrupts the gut microbiota and intestinal barrier, which decreases the production of beneficial microbial metabolic byproducts and allows for translocation of pathogenic bacterial-derived byproducts into the portal-hepatic circulation. As ethanol is known to damage liver sin...

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Bibliographic Details
Main Authors: Yingchun Han, Bryan Glueck, David Shapiro, Aaron Miller, Sanjoy Roychowdhury, Gail A. M. Cresci
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/12/2/373