Aberrant Single Exon Skipping is not Altered by Age in Exons of NF1, RABAC1, AATF or PCGF2 in Human Blood Cells and Fibroblasts

In human pre-mRNA splicing, infrequent errors occur resulting in erroneous splice products as shown in a genome-wide approach. One characteristic subgroup consists of products lacking one cassette exon. The noise in the splicing process, represented by those misspliced products, can be increased by...

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Bibliographic Details
Main Authors: Markus Lamla, Josef Högel, Dieter Kaufmann, Ralf Kemkemer, Kevin Mellert, Michael Uhl
Format: Article
Language:English
Published: MDPI AG 2011-08-01
Series:Genes
Subjects:
Online Access:http://www.mdpi.com/2073-4425/2/3/562/